Lupron flare protocol egg quality. Reply. Three days following the last OCP, lupron 20 mcg b. /Nov 2016: 4th ivf cycle- EPP-AFC:5, retrieved 10, 10 mature, 8 fertilized with ICSI, 6 blastocysts biopsied and frozen. This increase in FSH, along with the FSH we give you in your medication will help stimulate your ovaries. The second cycle, I did 10 units of Lupron twice a day the whole time. The term “Microflare” is derived in two parts: “Micro” refers to the use of a diluted dose of Lupron, micrograms instead of milligrams; and “flare” refers to the I have undergone 3 IVF cycles without success in Canada. 3 CCS normal embryos. “Long” GnRHa (Lupron/Buserelin/Superfact/Gonopeptyl) Pituitary Down-regulation Protocol: The most commonly prescribed protocol for GnRHa/gonadotropin administration is the so-called “long protocol”. The abnormalities appear to be random. He also suggested that I start taking metformin, even though I don't have PCOS or diabetes. While the flare protocol does not allow for a Lupron trigger to prevent OHSS, these patients don’t have a strong reaction to the gonadotropins (hence their modest egg retrieval numbers) and are seldom at risk to be overstimulated. Younger women or those with polycystic ovaries are usually treated with Lupron for approximately 10 days prior to beginning the shots of FSH. 3rd stim, 2nd retrieval: 5F, 5F, 5 day 5 blasts- all abnormal : (. GnRH-antagonist such as Ganirelix or Cetrotide. I’m 41 and did 3 cycles - the first was similar to your first and I got 14 eggs, 1 blast - euploid. 25 mL each night ( so 4 doses per vial). I think it really helped my egg quality. February 2013. The major difference is that, by cutting the dose of Lupron down to one sixth of the routine dose, and by giving it twice daily, the Lupron actually turns the pituitary gland IVF round 1 was a miserable failure with an almost cancelled retrieval and no embryos to freeze or transfer. This is important because one of the main strategies of fertility treatment is to get more EPP vs. Nov 30, 2015 · The first cycle ended up with a 2 cell embryo and transferred it anyway and BFN. There is no consensus on which protocol is the best treatment for all patients. I've had four embryos total from both cycles, but all unfortunately have turned out abnormal. Feb 25, 2022 · As an example, while small amounts of ovarian male hormones (predominantly testosterone) are essential to enhance egg and follicle development, over-exposure to excessive amounts of the same hormones can seriously compromise egg (and subsequently, also embryo) quality. Every follicle will not necessarily contain a quality egg. Norm also was my dhea, with the day, regular or the quality. First egg retrieval yielded no embryos for transfer, but I was also a very poor responder. Estradiol twice a day until period starts (if it starts during Ganirelix doses, stop then, though it's unlikely) Go in for baseline. Co-flare was moderately successful for me. Oct 29, 2021 · Long lupron; Lupron stop; Flare (NOT microdose lupron flare, this protocol included an endogenous FSH flare from clomid/letrozole treatment) They looked at a number of different IVF outcomes, and also at subgroups that had poor fertilization or blastocyst progression during their first cycle. This adds internal FSH to the external FSH in the gonal-f and can enhance how the ovaries respond…especially for people that had a lower response to the antagonist protocol. I have poor egg quality thanks to endo destroying my ovaries. ER2 estrogen priming and microdose (flare) Lupron protocol. Subsequent 2 IVF cycles were done in flare protocol. For round 2, my RE has suggested that we try a microdose lupron flare protocol (without BCP, to avoid over-suppression). I did the antagonist cycle first and had 5 eggs; with the 2 microdose lupron cycles I got 9 and 19 eggs, respectively. Hello. The LDL protocol was initiated with late luteal lupron (0. Jul 9, 2021 · My 1st cycle was traditional antagonist protocol and canceled due to lead follicle. FAQs from users Is the natural cycle a good option for poor responders? Jun 3, 2014 · Lupron’s role in this process is simply to interrupt the communication between the brain and ovary. IVF #3 - same as 2 - 10 ER, 8M, 5F, 4 made it to transfer Nov 3, 2020 · Fig. Thereupon, Lupron is overlapped with the BCP for 2-4 days. were initiated in patients receiving MDF. New York, NY 10021. Context: My doctor has decided to change my protocol for my 2nd attempt at IVF. Last year, tried again with the same protocol (Microdose Flare Lupron) but cycle was cancelled because my body was not responding. 2 came back normal but one With better chances. Jan 12, 2011 · Lupron flare, egg quality what now? - posted in Ask the RE: Hello, We just finished our first cycle, during which I somewhat overstimmed (16 eggs, sky-high E2 levels) but we got 3 good embryos, froze 1 and implanted 2 (my lining was 10. Key to table: Blood and ultrasound = blood test for hormone values ( estrogen levels in IVF stimulation are important) and transvaginal ultrasound to measure the follicle sizes in the ovaries. Acne. This is my protocol. Will work at a microdose lupron flare or the different. Trigger with pregnyl. With the long lupron down regulation protocol where the pituitary gland is largely exhausted of its LH and residual minimal LH is present in the circulation by the time The Microflare protocol consists of a combination of oral contraceptive pills (OCP’s), Lupron (diluted), and gonadotropins designed to maximize your ovarian response. Oct 1, 2012 · Yes if you have 20+ eggs retrieved an they grew really fast, their quality may have impacted by the high dose. Cycle 2: 6 eggs, 5 fertilized, 3 frozen blasts, 1 PGS normal. Stimmed for 12 days and had retrieval on day 14. Last cycle I was on max Gonal-F, max Ganirellix, and max low-dose HCG before the trigger. Then thee BCP is discontinued and daily Lupron therapy is Cycle 3 Microdose Lupron flare: Estrogen priming, 450 follistim 20-50 low dose hcg, Clomid, omnitrope, 10,000 HCG trigger, 12 retrieved, 8 mature, 8 fertilized, 5 blasts sent for testing (2 euploid) Cycle 4 Microdose Lupron flare: Estrogen priming, 450 follistim, 50 low dose hcg, Clomid, omnitrope, 10,000 HCG trigger, 17 retrieved, 13 mature Jun 16, 2023 · Purpose The objective of this study was to assess if very-low–dose Lupron (VLDL) and ultra-low–dose Lupron (ULDL) protocols can have comparable cycle outcomes when compared to other “poor responder” stimulation protocols based on POSEIDON classification groups 3 (PG3) and 4 (PG4). A “stop Lupron” protocol is one of the options to get a better ovarian response when using stimulating medications. I had 19 eggs retrieved, 13 were mature, and 9 fertilized. Egg/Embryo Quality: Reproductive age significantly impacts egg and embryo quality, and negatively correlates with IVF outcome. Two protocols I was put on to try to get more eggs were estrogen priming and co-flare. Good luck for cycle 2. My first IVF, we did estrogen priming protocol and I got 7R, 7M, 5F (with ICSI), froze 2, transferred 2. 88 and my AFC is normally 10-12. This one is kind of hard to read, but it shows improved outcomes with micro flare (birth control prime, Lupron cycle day 1 twice daily with a FSH like Gonal-F), are better overall, including egg quality. Unfortunately it is a bit of trial and error, there’s no universal best protocol that works for all DOR ladies! Good luck! This one is kind of hard to read, but it shows improved outcomes with micro flare (birth control prime, Lupron cycle day 1 twice daily with a FSH like Gonal-F), are better overall, including egg quality. This helps to control your ovulatory cycle and prevent premature Hi Donna. I do think a change of protocol can help. Microsoft Word - Schedule for Micro-dose Lupron Protocol 3. I tried a second IVF in May - I was split between whether to use antagonist or micro-dose. I just completed my 4th egg retrieval and used Omnitrope for the first time. 4 I did the micro dose lupron flare protocol. Stimulation phase: You’ll remain on Lupron; the dose is often lowered at this point. Round 2 - 10 eggs retrieved, 5 fertilized, 2 blasts both of which came back PGS normal! 300 Menopur and I think it was 300 Gonal, cetrotide, trigger with HCG and Lupron. Of those three we transferred, none were great quality. Are you about to start IVF? Are you wanting to learn more about the IVF process? Check out this video to learn more about the Microdose Lupron Flare Protocol Jan 25, 2009 · short protocolER: April 21/11- 8 eggs, 7 mature 5 embryosOn day 3: 4x4 cell grade 2 and 1x2 cell grade 15 day transfer of 1 blast on April 26/11 (two surprise blast frosties) Beta on May 6/11. Increased sweating or night sweats. This is important because one of the main strategies of fertility treatment is to get more The Microdose Lupron Flare Protocol is a type of ovarian stimulation protocol used in IVF treatments. 9 eggs retrieved, 2 fertilized with ICSI, 1 arrest on day 3, the other arrested on day 5. “Flare protocol” is another IVF protocol that is First 2 rounds I got the same stats as you minus the blasts. 8 ER, 5M - 1F IVF #2 - BCP (21 days), Micro dose Lupron flare, 300 Gonal F and 4 vials of Menopour, triggered with Ovidrel - 15 ER, 13M, 10F, 7 made it to ET. As for poor embryo quality, beyond getting better eggs and better sperm, one thing they can do is called co-culture. LPS vs. Upset stomach (including nausea or diarrhea) Breast swelling or tenderness. Isn't that kind of an aggressive protocol for someone with day 3 numbers like that? Couldn't that risk sacrificing egg quality to quantity? Ultimately we switched protocols and for my next cycle we tried the microdose lupron (flare) protocol. This review compares the agonist long protocol, antagonist protocol and minimal stimulation protocol. My "official" infertility diagnosis is Dysfolliculargenesis, which literally means my Dec 7, 2018 · I did 225 of Gonal-F twice a day (450 total per day), no menopur, and microdose hcg. Now is the perfect time to start your Baby Registry! START A REGISTRY Guides 21 E 69th Street. There are 2 classes of drug used for this: GnRH-agonist (gonadotropin releasing hormone agonist) such as Lupron. Generally people being recommended donor after 1 cycle are getting between 0-2 eggs, and are over 40. My dose was mix 1 mL of diluent with 5. We're going to do a second round with my next menstrual cycle, and my doctor has changed my protocol to the Schoyer Lupron Flare Protocol. MDF). 🤞🏻 I was considered a poor responder with the first Antagonist cycle and it took me a lot longer than my RE's average patient. If you have much more , they quality may have impacted. My second and third ERs they wanted to cancel because I was only showing one leading egg. Mar 17, 2015 · The overall CPR when using flare protocols in POR has ranged between 12% and 26. Oct. Sep 21, 2020 · 1. I've been on both the antagonist and microdose lupron flare protocols. Although there is no evidence this protocol is better Microdose and flare are the same thing. Gonadotropin-releasing hormone (GnRH) antagonist and minimal stimulation protocol has shorter duration of treatment and less German hospital and sign the micro lupron first few eggs will my chance for testing are the us. Cycle outcomes (total oocytes retrieved, fertilization rate, and total embryos frozen) between each phase of DuoStim and MDF cycles were compared via one-way ANOVA (FPS vs. Sperm factors. Of the flare cycles, first one was using Gonal F (450IU) and Luveris, we got 18 eggs, 13 mature, all 13 fertilized, but on day 3 only 2 had divided to 6-8 cells. When administered this way, the Lupron® stimulates your pituitary to make more FSH, followed by suppression of ovulation. Changed clinics and new Dr said Microdose Lupron causes poor quality embryos. If you have much less, there is not much to work with. This stim was 6 days longer than my previous cycles which were both 10 days. I have done several standard cycles, a mini IVF round, duostim and micro dose lupron flare - the micro dose lupron flare resulted in most eggs retrieved and best maturity/fertilization/blast rate of them all. com Sep 21, 2020 · The flare protocol is used to “jump start” ovarian response to stimulation in poor responders, in women of advanced reproductive age, and in women with low ovarian reserve. EPP was an utter disaster for me, but, has worked wonders for many other women. The Microflare protocol consists of a combination of oral contraceptive pills (OCP’s), Lupron (diluted), and gonadotropins designed to maximize your ovarian response. Phone: 626-385-7918. Jul 25, 2012 · In general, the long protocol takes between 17 and 21 days from the time that Lupron is started until the eggs are retrieved. He said that sometimes even in women without PCOS, lowering insulin resistance leads to improved egg quality. Protocol was slightly different - second protocol was a Lupron Flare protocol so a longer and slower stim. Jul 9, 2012 · Jul 9, 2012 at 1:07 PM. It involves the administration of a small dose of the medication Lupron, followed by FSH injections. Fatigue. You use microdose Lupron to “flare” your bodies natural production of FSH. Jun 14, 2020 · I did my ivf in June/July 2018. We are really disappointed to have gotten so few embryos. Leuprolide is a gonadotrophin-releasing hormone (GnRH) agonist. IVF stimulation protocols in the US generally involve the use of 3 types of drugs: A medication to suppress the LH surge and ovulation until the developing eggs are ready. Embryo transfer. What felt "cookie cutter" was that despite my great day 3 tests, RE put me on microdose Lupron flare protocol with 300 units of Follistim (150 twice a day). Fax: 212-994-4499. I got 2 second opinions and they wouldn't use this protocol. Methods A retrospective cohort study at a single, large academic center was performed. It reduces the amount of hormone that stimulates ovulation. It was a rocky start (I did not have uniform growth), but at my ER they got 11 mature eggs (I think I had 13 follicles but not sure). June 2011: On the waiting list for adoption from South Korea. 36 hours prior to egg retrieval: You’ll stop injections prior to the hCG “trigger shot,” which induces the final maturation of the eggs. Cycle 1: 8 eggs, 6 fertilized, 4 frozen blasts, 1 PGS normal. d. See full list on theluckyegg. These visits usually take about 20-30 minutes in our offices and can be scheduled as early as 6:30AM. 8 mg vial and inject 0. doc. For our first ivf, I did lupron, 300iu of follistim and 1 vial of menopur for 9 days. IVF #1 - No BCP, No Lupron, 300 Gonal F and 3 -4 vials (went up and down) of Menopour, triggered with Ganerilex. Jul 13, 2020 · I didn’t do BCP but did use omnitrope. I used Lupron once successfully at 41 but then two years later when I tried again, I had terrible results. T: 901-747-2229 F: 901-747-4446. 10 days after positive OPK, start estradiol (today, 2 doses 12 hours apart) Following 3 days, take estradiol twice a day, and 1 shot of Ganirelix in the evening. Stimmed for 11 days, got 16 eggs, 10 mature, 5 fertilized, no blasts. Special offers from the microdose protocol and patients did the We are completing both PGT-A and PGT-M, so do not have high hopes that our one fine quality embryo will be usable. 2 weeks bcps, microdose lupron morning and night, 300 IU gonal f in the am, 150 IU gonal f + 150 IU menopur in the pm. 17 eggs, 11 mature, 10 fertilized, awaiting day 3 results tomorrow. Second cycle was microdose lupron flare protocol. 8. 3% (4, 5). The other meds were the same. microdose lupron protocol (for DOR) BootsOrHearts member. Many women find that the side effects experienced while on Lupron, and during ovarian stimulation, are very similar to those they encounter during their normal menstrual cycle. My amh was . The dr said generally it is longer than the antagonist protocol. Which both I and my RE were REALLY happy with given my age (39) and AMH (0. It follows that protocols for ovarian stimulation should be geared towards Jun 14, 2020 · Round 1 - 8 eggs retrieved, 6 fertilized, 1 day 5 blast that came back abnormal. 2nd cycle, ended up with 5 mature and fertilized eggs; then 2 made it to Day 5 (a blastocyst and a merola) and I got my DS. This last round we primed with Estrace, did microdose lupron flare protocol, and added in a few doses of omnitrope. I feel like I got a bit of a "cookie cutter" treatment from current RE and am wondering what changes you Nov 25, 2021 · Lupron is a GnRH agonist used as a potent fertility medication to stimulate the pituitary gland in the short term and suppress it in the long term. If 70% were immature, they should be considering a double trigger (eg lupron and HCG). ” It’s a lot of days of stimming (14 days) and a lot of meds (450iu/day of gonal and 150 of menopur), but I went from having 3 follicles and a canceled cycle with the standard protocol to 12-15 follicles, 7 mature frozen eggs per cycle with two rounds on the flare protocol. "Empty follicles" is a very poorly defined thing. 2. Trusted Infertility Specialists serving Upper East Side New York, NY. MDF protocol consisted of a single ovarian stimulation cycle with microdose Lupron and recombinant FSH with hCG trigger, followed by oocyte retrieval. Since my issue is strictly endo based, a supplement won't do anything for me. I just replied to another post on this, but I thought it warranted its own post. 2 Microdose lupron flare protocol (MDF) Fig. I had good results with a lupron flare protocol. #5. i. In case donor eggs were needed, you should expect prices from $20,000. You can’t use lupron as a trigger if you’re doing an agonist cycle though. Jan 14, 2020 · Flare, or Micro-dose Lupron Protocol: In women who are of advanced maternal age, or for those who’ve had a poor response to other protocols, your fertility specialist may recommend this protocol, involving a lower dose of Lupron which will be started at the same time as the FSH injections. I decided to try to bank 4 embryos to give myself the best chance. Is Microdose Lupron the same as leuprolide? Micro Dose Lupron Micro-dose leuprolide acetate, which is compounded in the pharmacy. Hello - I am wondering if anyone with poor egg quality/low egg reserve has had success with the flare protocol? My doctor wants to try this next round after the first round failed using just gonal-F and menopur in an antagonist cycle. During an in vitro fertilization (IVF) protocol, your doctor may use leuprolide (Lupron) injection as part of an ovarian stimulation regimen. After a first round failure after retrieving 25 eggs, For my 2nd and 3rd retrievals I did the longer protocol starting with birth control and Lupron. 2nd stim, 1st retrieval: 11 follicles, 9 eggs, 6 fertilized, 4 blasts, 1 normal. I started on 300 IU gonal f per day then upped that to 375 IU per day since I was responding slowly. The goal of this protocol is to stimulate the ovaries to produce multiple mature eggs for retrieval during the IVF process. This accomplishes two things; First, it prevents the brain from selecting just one egg from the available group of eggs at the beginning of the cycle. 225 menopur and 450 Gonal F. 2 if I recall correctly), but they didn't take. Shitty egg quality seems to be our problem since I make decent numbers of eggs at high doses. Live birth rates are 50% in women less than age 35 and approximately 25% in women between the ages 40 to 42 per fresh IVF cycle. Jan 29, 2020 · Omnitrope (HGH) protocol / dose. However, some reports on outcomes using a decreased dose of GnRH-a (the so-called microdose flare protocol) have revealed conflicting results in cycle cancellation rate (CCR) and CPR despite improved cycle outcomes (3, 6). I only retrieved 4 mature eggs the first time. 9/2016: 3rd ivf cycle-cancelled due to early ovulation. flare protocols” can harm egg/embryo quality and reduce IVF success rates Apr 17, 2016 · Lupron Flare/Micro-Flare Protocol: Another approach to COS is by way of so-called “(micro) flare protocols”. I I have done several standard cycles, a mini IVF round, duostim and micro dose lupron flare - the micro dose lupron flare resulted in most eggs retrieved and best maturity/fertilization/blast rate of them all. In this protocol, Lupron will be used at the lower dose of 5 units daily instead of using 10 or 20 units, and then it is completely stopped after the woman gets her period. None to freeze. While they are generally safe for younger women with normal ovarian reserve, I personally avoid using this approach on the off chance that even patients with normal ovarian reserve, might experience poor egg quality. If you have questions about IVF protocols or about fertility treatment in general, feel free to contact one of our fertility specialists at (818) 881-9800. That being said, I had a successful IVF cycle, my first, in 2010. My response was WAY better. Switched to a lupron flare for the next 2 and got 15 and 16 eggs, 2 and 4 blasts - the 2 from the second were both inconclusive but 2 of the 4 were euploid. Unfortunately it is a bit of trial and error, there’s no universal best protocol that works for all DOR ladies! Good luck! Oct 27, 2014 · zeynsom member. Apr 10, 2016 · Lupron Flare/Micro-Flare Protocol: Another approach to COS is by way of so-called “(micro) flare protocols”. Endo has literally eaten away my right ovary and damaged my left. Some very good doctors believe that Lupron isn't great for egg quality in women over 40 or those with higher FSH. I had 13 days total of stims, got 11 eggs, and no viable embryos. 80 Humphreys Center, Suite 307 Memphis, TN 38120. Blood for pregancy test. In addition, reduction of immature oocyte syndrome is as a result of GnRH-a trigger Jan 16, 2024 · Key Points. In my first (and failed) IVF cycle I did microdose lupron flare. Sometimes it can be due to having ovulated early (which as far as I know has nothing to do with egg quality) The first cycle was the long lupron protocol, just like the one your RE planned for you. Once down regulation was obtained, the lupron dose was decreased to 0. I only got one normal embryo Second cycle they switched it up and did a mid luteal longer protocol no birth control. First IVF using long protocol, failed to stim and the cycle was cancelled. 375-450IU Gonal, 250mcg Ganirelix, 20-50units low dose HCG, pregnyl trigger. Continuing lupron screening test, and its main disadvantage is to. 3 Antagonist Cycle (ANT) In the following text, the various factors within an individual protocol that can affect cycle response in patients with POR will be reviewed such as FSH dose, use of augmentation agents growth hormone (GH), dehydroepiandrosterone (DHEA) and testosterone,… Anecdotally, talking with other women with DOR who have done multiple rounds, they see a difference between protocols and mostly prefer the lupron microflare, but it typically is only a few eggs difference. I had 10 follicles (5L 5R) in my baseline check. 28). During this time, most patients have 6-8 visits with their doctor. High levels of LH can lead to poor egg quality, premature ovulation, and stimulate progesterone production by the ovaries. IVF#2 was the micro dose flare protocol. I stimmed for 16 days that cycle and pushed past 2 lead follicles before the ER. The decrease in the success rates with IVF or any Jan 14, 2011 · What felt "cookie cutter" was that despite my great day 3 tests, RE put me on microdose Lupron flare protocol with 300 units of Follistim (150 twice a day). As women lose eggs due to aging, it can be hard to stimulate ovaries to produce enough follicles and eggs for a good chance for success with in vitro fertilization. Jan 28, 2012 · Mar 1, 2013. 1 Long Agonist protocol Fig. Another regimen is the flare protocol, where Lupron® is started after your menses on day 2. Called the “flare”, the “microdose flare”, or the “low dose Lupron” protocol, this regimen uses the same medications as the “Lupron overlap” protocol. Had higher AFC this month. Apr 11, 2022 · On the other hand, only the medications used for the microdose lupron flare protocol can cost up to $5,800 plus the costs of the IVF treatment itself. Isn't that kind of an aggressive protocol for someone with day 3 numbers like that? Couldn't that risk sacrificing egg quality to quantity? response. 25 mg daily). Total of 12 mature eggs and 1 poor quality embryo from those rounds. The term “Microflare” is derived in two parts: “Micro” refers to the use of a diluted dose of Lupron, micrograms instead of milligrams; and “flare” refers to the I’ve had much better luck with the “microdose lupron flare protocol. 13R, 11M, 5F with ICSI - 3 abnormal blasts. Given its wide array of medical uses, the use of Lupron is beneficial for a variety of IVF protocols, including: long luteal, microdose flare, frozen embryo transfer, and as a trigger shot. It’s just a case of trying a variety of protocols and different things to see what works. The mircrodose lupron protocol I did the retrieval on day 12. For patients who are taking BCPs, the flare protocol microdose starts after the BCP regimen is complete. Menopur and gonal f with cetrotide and lupron trigger. ER3- went back to antagonist protocol with estrogen priming, clomid and dual trigger. I responded quite slowly and over time 5 follicles on the right disappeared. 10 units of lupron in the am and pm, 300 gonal-f in the am, 300 menopur in the pm, then trigger. The second was lupron flare with synerall and 300 units of gonal f and we got 9 eggs and 3 embryos (day 5). flare protocols” can harm egg/embryo quality and reduce IVF success rates My first retrieval they had me on birth control then menopur and gonal f with cetrotide and lupron trigger. Apr 9, 2015 · Many stimulation protocols are available for controlled ovarian hyperstimulation (COH) in in vitro fertilization (IVF). I was also on 350 gonal and 150 menopur and doing the microdose Lupron flare protocol after estrogen priming. Here, GnRHa is given, starting a week or so prior to menstruation. BFN. I had 2 egg retrievals with antagonist protocols on day 10. I stimmed a little longer than most, 13 days I think. Age 38 at the time. 1. I would be asking what the rationale is for that protocol, it might increase quantity but if they’re not maturing with the right trigger then it seems pointless. I agree with the previous posters that it's a good idea to ask about Antagon and EPP protocols. I was on 450 IU gonal f and 150 IU menopur per I've just done my second IVF cycle, trying for baby #3! I used micro-dose flare. Jun 9, 2023 · In this way, these “flare protocols” can potentially decrease the success rates of IVF. I second this, the first cycle I did was antagonist and cancelled due to poor response (2 eggs). 300 iu Follistim + 150 iu Menopur + oral steroid . Because GnRH agonist can induce an initial “flare-up” effect, the short GnRH-a protocol is usually provided to poor responders to avoid excessive pituitary suppression . May 2014. One week before ovarian stimulation: You’ll start Lupron injections now, usually after natural ovulation has occurred. Most clinic aim to have 10-15 eggs , because that is a good balance between quality and quantity. Recent modifications of luteal phase after GnRH-a trigger make it possible to transfer embryo in the same cycle for many women at the risk of OHSS and provide a good outcome (7, 8). People's results can vary drastically from cycle to cycle. My AMH is . I only had 4 mature eggs and only 2 of those made Apr 24, 2021 · I also had egg quality issues during my 3 retrievals at 38 years old. 125 mg daily and gonadotropin stimulation was initiated. Upper East Side. Contact us at 626-385-7918 or visit us at 21 E 69th Street, New York, NY 10021: Center for Human Reproduction. Women in PG3 (age Mar 1, 2001 · In addition, whether the use of the microdose flare protocol in women with FSH >12 IU/l and small ovarian volume can improve the low pregnancy rate in these women remains to be investigated even though we believe that, by the time both ovarian volume and FSH become abnormal, very little can be done to change the outcome of these women, other Apr 27, 2023 · At the beginning of a new menstrual cycle—and before starting controlled ovarian stimulation (COS)—priming begins with a flare protocol, which includes a microdose of the gonadotropin releasing hormone (GnRH) agonist Lupron®. One specifically I am heading into my third round of IVF and my RE now wants to put me on a mini stim protocol. Isn't that kind of an aggressive protocol for someone with day 3 numbers like that? Couldn't that risk sacrificing egg quality to quantity? Dec 19, 2015 · In the past, this protocol was followed to freeze all embryos in many cases. We transferred 3 on day 3 and had none to freeze. The other difference was that we added omnitrope during days 4-8. Aug 22, 2018 · Use of Lupron to launch Ovarian Stimulation for IVF: At Sher-IVF we launch controlled ovarian stimulation (COS) for IVF by putting the woman on a birth control pill (BCP) for 10-25 days, to suppress ovarian response to FSH/LH. Mar 18, 2018 · 3/2016: RE suggested donor eggs- taking an ivf break and to supplement. During an egg retrieval, your doctor will aspirate the follicles with an ultrasound-guided needle. Jan 7, 2010 · The ovaries may be sensitive to LH and where excessive exposure of follicles and eggs to testosterone could severely compromise egg development and thus embryo quality. My first IVF was the long lupron protocol, I got 6 eggs from 7 follies, 4 fertilised, & one 'perfect' 8-cell was replaced on Day 3. 4th stim, 3rd retrieval: 4 follicles, 1 giant cyst- 1 egg retrieved, it apparently fertilized abnormally, but made Jul 24, 2015 · The short GnRH-a protocol was suggested as an alternative protocol. I was on BCP first, then 20 units of microdose lupron (x2/day-- am, pm) and 300 follistim (x2/day, am, pm). Jun 3, 2014 · Lupron’s role in this process is simply to interrupt the communication between the brain and ovary. fx vv bh jd qc vd ri qo hs nc