Why is acetanilide soluble in water. The more alike the solute and solvent in terms of polar character, typically the greater is the solubility of the solute in that solvent. 6. However, acetanilide is only slightly soluble in water. 70 solubility advantage CHM2211L Exam 1. Draw the structure of acetanilide and explain why this compound is only partially soluble in cold water. It is hygroscopic in nature and easily soluble in water. 0. Explain why water was an appropriate solvent to use for recrystallization in lab. In the case of aqueous 1,4-dioxane mixture the synergistic effect occurred at x 2 * = 0. Aniline, the parent compound of aniline hydrochloride, is a basic compound and will undergo acid–base reactions. In addition, there are no internal stabilizing structures that favor In a 50 ml erlenmeyer flask, 1. a) Identify one structural feature of the acetanilide molecule thatwould be expected to contribute positively to itssolubility in water. The H+ ion is much less electronegative than the Cl- ion , so the Cl- ion pulls electrons towards itself in the chemical The crude acetanilide was weighed. Solution :- Following image shows the structure of …. Despite the fact that the phenylamine is only a very weak base, with a strong acid like hydrochloric acid the reaction is completely straightforward. The dividing line is four carbons. Question: Acetanilide is not particularly soluble in water. A. concentrated sulfuric acid and then mixed in an ice bath. A solvent is simply a substance that can dissolve other molecules and compounds, which are known as solutes. 53 g/100 mL at 0 °C. Remove test tubes from the hot water bath and place them in the test tube rack to cool. 41b), the crystallized solid was still a pure white color (Figure 3. Well, this was just a simple answer. NaOH, B. Because of its polarity and ability to form hydrogen bonds, water Learn more about this topic, chemistry and related others by exploring similar questions and additional content below. Properties. These three organic solvents mutually saturated with water, and finally, in cyclohexane. Since o-nitroacetanilide is very much soluble in alcohol it is very easy to isolate p So do intermolecular interactions explain everything about solubility? Do they explain the differences between the solubility of hexane, hexanol, and hexanediol in water? Hexanediol ( HO(CH2)6OH H O ( C H 2) 6 O H) is readily soluble, and if we consider its structure we can see that interactions between hexanediol molecules include hydrogen bonding (involving the two hydroxyl groups) and van An acid-base extraction can be used to extract carboxylic acids from the organic layer into the aqueous layer. When acetanilide is treated with a nitrating mixture, i. Show transcribed image text. activated carbon 3. Acetamido group, being a bulky group, will cause the steric hindrance at the position of ortho. Molecules which are capable of hydrogen bonds have hydrogen atoms which are covalently bonded to highly electronegative elements (O, N, F). Acetanilide is a substance that is soluble in hot water, but not in cold water. The solubility of octan-1-ol is 0. The Solubility of Compounds: Compounds whether organic or inorganic (ionic) have varying degrees of solubility in various solvents. . The solubility of pentan-1-ol is 2. 07 = ( x 50mL ether) ( 0. Yes, water will completely dissolve HCl because HCl is a strong acid. The presence of hydrogen bonding between molecules of a substance indicates that the molecules are polar. This problem has been solved! You'll get a detailed solution from a subject matter expert that helps you learn core concepts. Explain how aniline is a base. Jul 31, 2021 · Preparation of Nitro Compounds. Q 1. Thing is, I lost like 70% of solid, so I was (am) kind of in denial, but I think is the only explanation. Typical problems: Adding too much solvent so that the product does not crystallize later. Jun 24, 2012 · Dr. Explain why Tetrahydrofuran is soluble in water but hexanes is not? Explain why triethylamine, (CH_3CH_2)_3N, is very slightly soluble in water but readily soluble (with stirring) in 1. This indicates a possibility of predicting solubility changes for the remainder of the compounds if the solubility change for one of the compounds is known. What would be the maximum theoretical percent recovery (first crop only) from the c Question: assuming you have 1. Based on your answers to question 2, redraw and complete the diagram below modeling 8 years ago. However, if the mixture contains a desired compound that can react with NaOH, a milder base Exposure characterization. CH3CH2CH2CH2CH2CH2OHHexanol CH 3 CH 2 CH 2 CH 2 CH 2 CH 2 OH Hexanol. Let the test tubes cool to room temperature. Aniline is primarily produced by catalytic reduction of nitrobenzene. Some commonly used solvent pairs are water-ethanol, acetic acid – water, ether-acetone. The solubility changes obtained for acetanilide and the several para derivatives were found to show a fair correlation with respect to the magnitude of solubility in water. 2 The polar nature of acetone allows it to form hydrogen bonds with water molecules, enabling the mixing and dissolution of acetone in water. Nov 21, 2023 · Acetanilide is slightly soluble in water. 6 mL of acetic anhydride and prepare a solution of 530 mg of sodium acetate in 3 mL of water. Then, 0. Was this answer helpful? 1. Acetyl salicylic acid is soluble in ethanol but very poor soluble in water , this is due to fact Compared to water, ethanol has a hydrophobic carbon chain. What is the trend in solubility for alcohols in water as the number of carbons in the parent chain increases. 7 ml of cold concentrated nitric acid was combined with. ethanol 4. Aniline, a potential impurity, is more soluble in room temperature water. Jul 3, 2021 · In the case of the former binary mixture, the highest phenacetin solubility was observed at x 2 * = 0. 5 g/100 ml at 100 oC) is not very great, and its solubility in cold water (0. Check the solubility of 128 common inorganic compounds (salts and acids) in water at different temperatures from 0 degrees Celsius to 100 C. Boiling Point: The boiling point for this substance is 304 °C. While still hot, the solution was filtered through the filter paper. Rinse the flask with 3 mL of water, disconnect the suction tubing, pour the rinsing into the funnel Feb 24, 2022 · You have not visited any articles yet, Please visit some articles to see contents here. We would like to show you a description here but the site won’t allow us. Cinnamic acid is soluble in ethanol and has very low solubility in water. How to perform a recrystallization: The crude impure solid is dissolved in hot solvent. Chemistry. Lennox. Yes, acetone is soluble in water. 3 ℃. When recrystallizing a solid, it's best to wash the Dec 1, 2004 · more soluble in the water-saturated octanol. It has oxygen. To address this, start by creating a saturated solution of acetanilide in boiling water. 53 g/100 mL at 0 degree C) is not very great. e. Why is octanol soluble in both water and hexane? 4. However, when heated, acetanilide becomes soluble in water. Nitro compounds can be prepared in a number of ways, including the direct substitution of hydrocarbons with nitric acid, [Math Processing Error] (24. 1 It is soluble in water because acetone and water are both polar molecules. What allows some organic compounds to be soluble in water? 2. 3. Q. The solution was heated in the water bath until the solid dissolves. The organic compound p-nitroacetanilide is prepared from acetanilide through nitration. Why aniline is less soluble in water. Addition of water can rapidly and dramatically reduce the solubility of many organics and thus induce crystallization. Also, as a minor product, along with p-nitro acetanilide, o-nitro acetanilide is formed. In this case, then, the solubility in 5% sodium hydroxide solution of a water insoluble unknown is a strong indication of an acidic functional group. will be soluble in water due to formation of s …. This suggests that it gets dissolved in water at a higher temperature. So, we use a mixture of 95% ethanol and 5% water so that cinnamic acid is still soluble at high temperatures but less soluble at low temperatures. 53 g/ 100 ml at 0 oC) is significant. 1: Solubility in Water. Phenylamine reacts with acids like hydrochloric acid in exactly the same way as any other amine. Finally, make an ice bath, by putting ice in a 250 ml beaker and filling the beaker up with water. Weigh the dried solid and calculate the mass of pure acetanilide by difference. 10. Paracetamol has a very low solubility in nonpolar and chlorinated hydrocarbons such as toluene and carbon tetrachloride whereas the solubility is very high in solvents of medium polarity such as N,N-dimethylformamide, dimethyl sulfoxide, and diethylamine. Does Salt dissolve in HCL? Yes, salt (sodium Jan 15, 2018 · In this work a solid-liquid equilibrium model was applied to predict the solubility of acetanilide and its derivatives in water. Question: Following is the molecular structure of acetanilide. Methanol, ethanol, and propan-1-ol are infinitely soluble in water. Once the unknown was purified, the purity of this sample could be tested by mixture melting point. It is also soluble in diethyl ether, ethanol, benzene and acetone. 726 in mole fraction [29] ); elsewhere, the role Aug 19, 2006 · The thermodynamic functions free energy, enthalpy, and entropy of solution, were evaluated from the solubility data of acetanilide, acetaminophen, and phenacetin, determined at several temperatures in water, octanol, isopropyl myristate, and chloroform. 2. 05g. EQC model of fugacity level I shows that the chemical will be distributed mainly to water. Click the card to flip 👆. Similar Questions. Give a step-by-step description of how you would purify the acetanilide by water. Aniline is sparingly soluble in water but it is soluble in aqueous HCl. 50g acetanilide from nearly boiling ethanol. Mar 31, 2009 · The solubility of both aniline and acetanilide in aqueous HCl is affected by temperature, pH, and the concentration of the acid. 1. Jul 22, 2023 · By Jay Rana / Last Updated On: July 22, 2023. Get a hint. Jan 27, 2021 · Acetanilide is approximately 10x more soluble in diethyl ether (1g dissolves in18ml) than in water (1g dissolves in 185ml). . A homogeneous mixture of solvent and solute is called a solution, and much of life’s chemistry takes place in aqueous solutions, or solutions with water as the solvent. 1 / 162. It has the ability to self-ignite if it reaches a temperature of 545 °C, but is otherwise stable under most conditions. Hydrolysis of the acetic anhydride is a competing reaction to the amidization. iodoform test for a. The results of the calculations in this section are summarized in Figure 4. Jan 23, 2023 · Phenylamine reacts with acids like hydrochloric acid in exactly the same way as any other amine. Yes, acetanilide is soluble in most organic solvents such as ethanol, methanol, and chloroform. Solution : Following the structures of the anil …. Sodium Acetate(CH3COONa)- Sodium acetate is the salt of acetic acid and sodium hydroxide. Along with p-nitroacetanilide, o-nitroacetanilide is also formed as a minor product. 5 g/100 mL at 100 degrees C) is significant and its solubility in cold water (0. 3 °C. If the hot ethanolic solution containing these two components is then cooled in an ice bath, acenapthene should crystallize as it has low solubility in cold ethanol. Because sugar is insoluble over a rage of temperatures, acetanilide will crystalize out as water cools and the sugar will remain in the solution. The compound is only partially soluble in cold water but readily soluble in hot water. Transfer the solid and filter paper to a pre-weighed watch glass. Solution for Is acetanilide soluble in ethanol: (1) at room temperature? (2) after heating? (3) upon cooling? Nov 21, 2023 · Acetone is a general, versatile, polar solvent. Many people call this "insoluble". If two solutions are insoluble with each other, describe how a mixture of the two solutions would appear. Page ID. In this section, we will concentrate on solubility, melting point, and boiling point. Place the bath and flask in the hood and add, in five or six portions, 25 mL of concentrated aqueous ammonium hydroxide; swirl in the ice bath after each addition. 100% (3 ratings) Question: Draw the structure of acetanilide and explain why this compound is only partially soluble in cold water. Since o-nitro acetanilide is much soluble in alcohol, it is so easy to dissociate p-nitro acetanilide by crystallization. This is the solvent you want to use for recrystallization. The most widely used solvent is water. 2) RX + NO 2 − → RNO 2 + X −. 1) RH + HONO 2 → RNO 2 + H 2 O. Explain the saying “like dissolves like” 4. In this sense, water can at best dissolve the carboxylic acid and polar portion of aspirin - a …. Acetanilide is prepared from aniline when it reacts with acetic anhydride/glacial acetic acid in the presence of zinc dust. Then explain how acetanilide is not basic even though it is produced from aniline. Molecular Weight: Its molecular weight is 135. 9741g acetanilide. 7 ºC, boiling point 304 ºC at 760 mmHg, water solubility g/L at 20 ºC, Log Pow 1. It is usually odourless but when heated to decomposition it smells like vinegar or acetic acid. Here’s the best way to solve it. This result means 0. Acetanilide is moderately soluble in hot water and hence can be recrystallized from boiling water by cooling it. Expert-verified. A. You say cyanidine is not polar due to being made only of hydrogen and carbon, but then talk about it having OH groups. Purification of this mixture works well in theory because the acetanilide is so much more soluble (approximately ten times as much) in the cold ethanol than Jan 23, 2021 · Solubility: Acetanilide is a little soluble in water. It is only the carboxylic group that is polar. Chemistry questions and answers. 100% (1 rating) Divide the molecule in two parts Large phenyl gro Because charcoal is insoluble, the mixture can be heated and the charcoal can be removed. ility. While acetanilide is soluble in ethanol at room temperature, it cannot be used as a solvent for recrystallisation. Share. 4g of unknown recovered from exp2 (organic lab 1) Identifying a constituent of panacean) what are the minimum amounts of cold and hot water needed to dissolve that mass of both acetanilide and phenacetin? why is phenacetin water solubility different than that of acetanilide. The model requires fusion enthalpy, fusion temperature, and activity coefficients of the acetanilides. 16 at4 23 ºC. Explain why the crystals were gray and describe steps that you would take to obtain a colorless product. crystals, although the compound was reported to be colorless. View the full answer. 5 M HCl. Paracetamol May 20, 2020 · Aspirin is a white solid compound, soluble in diethyl ether, acetone and ethanol, poorly soluble in water (3 mg/mL at 20 °C), benzene and even less soluble in propylene glycol. 5 \: \text{mL}\) of hot ethanol. 5. 054 g/100 mL. An understanding of bond dipoles and the various types of noncovalent intermolecular forces allows us to explain, on a molecular level, many observable physical properties of organic compounds. Apr 24, 2019 · Would acetanilide be more soluble in water at 25 degrees Celsius because it has an $\\ce{N-H}$ and an oxygen that can participate in hydrogen bonding, whereas diethyl ether only has an oxygen? Jan 28, 2015 · The present study used molecular dynamics with the General AMBER Force Field to predict the excess solubility of acetanilide, acetaminophen, phenacetin, benzocaine, and caffeine in binary water/ethanol solvents. Spread out the solid and carefully remove the boiling chips with tweezers. Why is aniline more soluble in aqueous HCl than in pure water? Note 1: In the Soluble at BP column, record “X”s for the solvents that were not tested Note 2: The acetanilide will dissolve in only of the samples at its BP. and acetanilide will be present in CH2Cl2 layer. The latter were predicted in the considered acetanilide + water mixtures with PC-SAFT. What would be Explain why acetanilide at room temperature has a low solubility in water but at the same time it is much better soluble in ethanol or chloroform. 05g) after the third extraction. Jul 27, 2020 · Why is ethanol used in recrystallisation? Ethanol/water combinations are commonly used because ethanol has good dissolving ability for many organics, but is also infinitely co-soluble with water. a mixture of nitric acid and sulphuric acid, it forms p-nitro acetanilide. For effective purification by recrystallization the compound must be much more soluble in solvent than in solvent, and the impurities must be either in hot solvent or in cold solvent. The compound is dissolved in a minimum amount of the hot solvent in which it is more soluble. Compound formulas are also given in this table of solubility in relation to temperature. 5 g/100 mL at 100 °C and its solubility in cold water is 0. The methyl red "impurity" remained in the mother liquor and was not obviously incorporated into the crystal lattice of acetanilide. Understand the structure of acetanilide including its functional groups, its various uses, its hazards, and how it is May 20, 2024 · Why is not acetanilide soluble in HCL? Wiki User. Phenylamine is only very slightly soluble in water, but dissolves freely in dilute hydrochloric acid. 09g − 0. 1 10. 4. The solubility of salicylic acid in ethanol and ethyl acetate acetanilide, synthetic organic compound introduced in therapy in 1886 as a fever -reducing drug. But not so soluble in water. May 21, 2024 · Water is a good solvent for recrystallization of acetanilide because acetanilide is more soluble in hot water than in cold water, allowing for the compound to be dissolved and then slowly Physical-chemical properties of acetanilide are as follows: melting point 113. This means the molecules will be soluble in a polar solvent such as What 4 reagents did we use with acetanilide? 1. Melting Point: It has a melting point of 114. 3. If some solid remains undissolved after adding solvent, it is likely to be an impurity and should be removed by filtrering the (hot!) solution. petroleum ether Acetanilide is (soluble/insoluble) in acetone at room temperature Aug 16, 2021 · Measure out 0. Explain why. The solubility of acetanilide in hot water is 5. The solubility of acetanilide in hot water (5. After dissolving in methylene chloride: Both compound will be dissolved and both B. How does temperature affect the solubility of acetanilide? The solubility of acetanilide increases with temperature, meaning that more acetanilide can dissolve in a given amount of water at higher temperatures. The solution becomes white as acetanilide precipitates. To learn more about Sodium Acetate Preparation, Properties, Uses and FAQs, Visit BYJU’S for a Nov 11, 1999 · The solubility of paracetamol (4-hydroxyacetanilide) in 26 solvents in the temperature range from −5 to +30 °C is reported. Activated charcoal is added to produce a colorless solution. The primary reason benzoic acid dissolves only slightly in cold water is that, even though the carboxylic acid group is polar, the bulk of the benzoic acid molecule is non-polar (water is polar). After adding aq. This compound is soluble in hot water. Add the acetic anhydride to the solution of aniline hydrochloride in water, mix by swirling, and immediately add the sodium acetate solution. Acetanilide is readily biodegradable (MITI test : 68. For example, benzoic acid is insoluble in a polar solvent, water, but is converted by 5% sodium hydroxide solution to a salt, sodium benzoate, which is readily water soluble. As was discussed in the previous section, NaOH can be used to convert a carboxylic acid into its more water-soluble ionic carboxylate form. Assume that you have an impure sample of acetanilide that contains charcoal and sugar. 7 g/100 mL. methyl carbonyl. 8 and was associated with a solubility advantage SA = 2. N-diethylaniline is not soluble in water? A: Diethyl amine is an aliphatic amine with formula of (C2H5)2NH while N,N - diethyl aniline is an… Q: Explain IR Unknown in Qualitative Analysis of Amines and Amine Unknown. Predict which of the following compounds will be most soluble in water: CH3CH2OHEthanol CH 3 CH 2 OH Ethanol. Account on the statement: Ethylamine is soluble in water, whereas aniline is insoluble. For amines one can take advantage of their basicity by forming the protonated salt (RNH 2+ Cl − ), which is soluble in water. ∙ 15y ago. 41c). acetone 2. Higher temperatures and lower pH levels tend to increase solubility, while higher concentrations of the acid can decrease solubility. 28), it should also completely dissolve in \(12. Because I recrystallized acetanilide in a water:ethanol mixture (30:1), then filtered it and washed it with 95% ethanol, trying to remove residual water. Source here As @Mithoron said in the comments, that phenyl group has a big effect. They're really soluble in boiling water but insoluble in cold water therefore impurities remain in the cold solvent after recrystallization and the desired elements (Acetanilide and Phenacetin) can be taken out by vacuum filtration. The boiling point of acetanilide is Solubility: Acetanilide is a little soluble in water. It is widely used across a number of industrial sectors. The main reason for the ab ove observation is the high solubility of water in octanol (0. The salt will extract into the aqueous phase leaving behind neutral compounds in the non-aqueous phase. Why? Draw the structures of ethyl acetate and hexane in your explanation. Acetanilide is more soluble in ethyl acetate than in hexane. Apr 29, 2017 · 4. 00g acenapthene and 0. Thus, the p-nitro acetanilide can be formed as a major product. Its pKa is 6. Why is acetanilide soluble in warm water, but trans-cinnamic acid is not? relate this to the ratio of total surface area to polar surface area- acetanilide has a higher ratio, how does this relate to why it is soluble while trans-cinnamic is not. Write a balanced equation for the hydrolysis reaction. The experimental solubility of salicylic acid in water and ethyl acetate was compared with the literature data. Acetanilide is soluble in acetone, ethanol, methanol, ether, and benzene. Explain why during the recrystallization of p-dibromobenzene, the turbidity of the hot solution was used as an yes. was added to Jun 5, 2014 · Molecules that can hydrogen bond with water have a higher solubility in water. Example 10. It is readily soluble in dilute mineral acids and bases. Butan-1-ol is partially soluble at 9 g/100 mL. Jan 15, 2018 · Knowledge about solubility in water is required for crystallization processes, for the development of structure-property relationships, for the establishment of solubility scales, assessing environmental contamination, and for validating thermodynamic models. Acetanilide is moderately soluble in hot water, but much lesssoluble in cold water. What kind of solubility does acetanilide have in water? Aniline forms the salt anilinium chloride which is water soluble. 09g − x 150 mL water) After solving the algebra, x = 0. It is a white, odorless crystalline powder soluble in water to the extent of 1:8,100 at 37°C and 1:13,000 at 25°C, in human serum to the extent of 1:620 at 37°C, and sparingly soluble in alcohol and acetone. 4 Solubility. Aniline and its hydrochloride salt will achieve a pH-dependent acid–base equilibrium in the body. A mixture of aniline, glacial acetic acid, acetic anhydride and zinc dust is refluxed under anhydrous condition and then poured the mixture into ice cold water to get acetic anhydride precipitate. Water is a polar compound and because May 21, 2018 · Primary Reason for Low Solubility. As one of the world's most commonly used medicine, aspirin is found in every pharmacy on earth as well as most supermarkets. This represents a crystallization with a "soluble" impurity. 6, reaching 2. Acetanilide can be produced by reacting acetic anhydride with either aniline or phenylammonium chloride. (btw, It was a test). 20mL of recrystallizing solvent was added to the crude acetanilide. Jul 15, 2023 · Since hexane is nonpolar, it is miscible with CCl 4, and so both form a single layer below the water. This answer is: the most suitable for recrystrallizing acetanilide is water. So that is two reasons why your initial suspicion of non-polarity because it is s simple hydrocarbon are wrong. That's definitely insoluble! must be miscible in one another. Its effectiveness in relieving pain was discovered soon thereafter, and it was used as an alternative to aspirin for many years in treating such common complaints as headache, menstrual cramps, and rheumatism. 31 in respect of water SA = log(X cosolvent /X water). Excessive or prolonged use engenders Question: Why is aniline soluble in aqueous HCl whereas acetanilide is not? Why is aniline soluble in aqueous HCl whereas acetanilide is not? Here’s the best way to solve it. 7 % after 14 days 4. 04g remains in the aqueous layer (0. Nov 17, 2023 · Sulfadiazine's plasma half-life is 17 hours. 18. Why was the crystallization completed in an ice bath? How would this procedure be detrimental to the production of acetanilide? Nov 21, 2023 · Learn about acetanilide. When the solvents start to boil, stir the solutions and record in your notebook whether the acetanilide was soluble or insoluble. It forms the salt anilinium chloride in aqueous HCl which is water soluble due to its polar nature. The aqueous layer is then treated with a base (NaOH) to regenerate the amine and NaCl. 17 g/mol. Since acetanilide (AT) is more soluble than acenapthene at this temperature (see Figure 3. Cool the solution in an ice bath and Dec 9, 2023 · According to the University of Wisconsin-Eau Claire, the C-C and C-H bonds are considered nonpolar, while other bonds are considered polar. Acetone has both polar and non-polar properties due to its polar bond (C=O) and non-polar bonds (C-CH3). Not only that but it is a charged species (also clearly shown on your structure). It is more soluble in organic solvents. Pure crystals are plate shaped, white in colour, and have a sugary Keep the vacuum on to dry the remaining solid for an additional 30 minutes, until solid is dry. Aug 10, 2023 · p-nitro phenol has a symmetric structure as compare to o-nitro phenol so it has higher dipole moment or polarity so is more soluble. The solid was crystallized from hot water without the use of charcoal, and even though the mother liquor was yellow (Figure 3. Also, when crystallised from ethyl alcohol, the p-nitro acetanilide crystallises mostly as colourless crystals, whereas, the ortho isomer remains in the same solution. The reason for the compound’s relatively low polarity is its aromatic ring; a significant part of the molecule exerts nonpolar characteristics. Typically, the compound being recrystallized will be more soluble in one solvent than the other. 7 しHou, are insoluuus impurities removed during a rec Science. 29: Crystallization of an impure sample containing 4. The melting point of acetanilide is 114. Aug 11, 2020 · Figure 3. Dec 12, 2007 · The solubility of salicylic acid in water, ethanol, carbon tetrachloride, ethyl acetate, and xylene was measured by a gravimetrical method from (298 to 348) K, and the solubility data were correlated against temperature. Availability. Aniline is insoluble in water because: Q. 19. Is acetanilide soluble in water: (1) at room temperature? (2) after heating? (3) upon cooling? Q: Why is diethyl amine soluble in water and N. The calculation for the third extraction is as follows: 4. Explain the cause of its poor solubility in cold water CHE A B IF. Collect the precipitated nitroaniline in a Büchner funnel by suction filtration. Less than 5 g of the compound dissolves in one liter of water. 6 ml of. When acetanilide is treated with nitrating mixture that is a mixture of nitric acid and sulphuric acid p-nitroacetanilide is formed. by displacement reactions with nitrite ions, [Math Processing Error] (24. yx xv dh hh nl zv rk gf wz qr